Stephan Wilmes

STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling

Kei‐ichiro Arimoto, Sara Löchte, Samuel A. Stoner et al. · Nature Structural & Molecular Biology · 2017 · 192 citations · Full text

Essential Adaptor, Cytokine, Signal Transduction +10

Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations

Stephan Wilmes, Maximillian Hafer, Joni Vuorio et al. · Science · 2020 · 181 citations · Full text

Receptor Dimers, Immunology, Molecular Biology +18

Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands

Ignacio Moraga, Gerlinde Wernig, Stephan Wilmes et al. · Cell · 2015 · 167 citations · Full text

Inflammation, Cytokine, Re-orienting Dimer Geometry +10

Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signaling

Stephan Wilmes, Oliver Beutel, Zhi Li et al. · The Journal of Cell Biology · 2015 · 129 citations · Full text

Molecular Regulation, Molecular Biology, Ifn-induced Dimerization +23

Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation

Ah Ram Kim, Jacob C. Ulirsch, Stephan Wilmes et al. · Cell · 2017 · 114 citations · Full text

Inflammation, Cytokine, Signal Transduction +12