Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity

Martin Corcoran, Ganesh E. Phad, Néstor Vázquez Bernat, +5

Nature Communications

Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach

Paola Martinez-Murillo, Karen Tran, Javier Guenaga, +16

Immunity

Particulate ArrayHuman RetrovirusImmunologyAntiviral ResponseVirology +3

High-Quality Library Preparation for NGS-Based Immunoglobulin Germline Gene Inference and Repertoire Expression Analysis

Néstor Vázquez Bernat, Martin Corcoran, Uta Hardt, +4

Frontiers in Immunology

Isolation of antibody V(D)J sequences from single cell sorted rhesus macaque B cells

Christopher Sundling, Ganesh E. Phad, Iyadh Douagi, +2

Journal of Immunological Methods

ImmunogeneticsJ SequencesHumoral ResponseImmunologyVirology +7

Enhanced HIV-1 immunotherapy by commonly arising antibodies that target virus escape variants

Florian Klein, Lilian Nogueira, Yoshiaki Nishimura, +17

The Journal of Experimental Medicine

Clonal structure, stability and dynamics of human memory B cells and circulating plasmablasts

Ganesh E. Phad, Dora Pinto, Mathilde Foglierini, +8

Nature Immunology

Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses

Sebastian Ols, Klara Lenart, Rodrigo Arcoverde Cerveira, +24

Immunity

VaccinationB Cell ResponsesB Cell ResponseVaccine DevelopmentNeurovirology +13

Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization

Christopher Sundling, Zhenhai Zhang, Ganesh E. Phad, +7

The Journal of Immunology

Adaptive Immune SystemHumoral ResponseImmunologyImmunodominanceMemory B Cells +17

Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds

Navid Madani, Amy M. Princiotto, David Easterhoff, +13

Journal of Virology

Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses

Ganesh E. Phad, Pradeepa Pushparaj, Karen Tran, +20

The Journal of Experimental Medicine

Adaptive Immune SystemHumoral ResponseImmunologyImmunodominanceCd4 T Cell Responses +20