Tapani Hyvönen

Monitoring of the uptake and metabolism of aminooxy analogues of polyamines in cultured cells by high-performance liquid chromatography

Tapani Hyvönen, Tuomo A. Keinänen, Alex R. Khomutov et al. · Journal of Chromatography B Biomedical Sciences and Applications · 1992 · 126 citations

Cultured Cells, Pharmaceutical Science, Biochemistry +7

1-Aminooxy-3-aminopropane, a new and potent inhibitor of polyamine biosynthesis that inhibits ornithine decarboxylase, adenosylmethionine decarboxylase and spermidine synthase

R. M. Khomutov, Tapani Hyvönen, Eira Karvonen et al. · Biochemical and Biophysical Research Communications · 1985 · 47 citations

Biochemistry, Medicine, Spermidine Synthase +5

1-Aminooxy-3-aminopropane reversibly prevents the proliferation of cultured baby hamster kidney cells by interfering with polyamine synthesis.

Tapani Hyvönen, L. Alakuijala, L C Andersson et al. · Journal of Biological Chemistry · 1988 · 45 citations · Full text

Embryo Culture, New Drug, Mm Spermidine +12

Polyamine synthesis in mammalian tissues. Isolation and characterization of spermidine synthase from bovine brain

Aarne Raina, Tapani Hyvönen, Terho O. Eloranta et al. · Biochemical Journal · 1984 · 45 citations · Full text

Synthesis of hydroxylamine analogues of polyamines

Alex R. Khomutov, Jouko Vepsäläinen, Alexander S Shvetsov et al. · Tetrahedron · 1996 · 41 citations

Organic Chemistry, Hydroxylamine Analogues, Synthesis Method +2