R. M. Khomutov

Monitoring of the uptake and metabolism of aminooxy analogues of polyamines in cultured cells by high-performance liquid chromatography

Tapani Hyvönen, Tuomo A. Keinänen, Alex R. Khomutov et al. · Journal of Chromatography B Biomedical Sciences and Applications · 1992 · 126 citations

Cultured Cells, Pharmaceutical Science, Biochemistry +7

Regulation of polyamine transport by polyamines and polyamine analogs

Debora L. Kramer, John T. Miller, Raymond J. Bergeron et al. · Journal of Cellular Physiology · 1993 · 66 citations

Spm Analog, Polyamine Transport, Biochemistry +14

Cellular characterization of a new irreversible inhibitor of <i>S</i>-adenosylmethionine decarboxylase and its use in determining the relative abilities of individual polyamines to sustain growth and viability of L1210 cells

Debora L. Kramer, R. M. Khomutov, Yuriy V. Bukin et al. · Biochemical Journal · 1989 · 63 citations · Full text

Molecular Pharmacology, Enzyme Active Site, Aldehyde Dehydrogenase +14

1-Aminooxy-3-aminopropane, a new and potent inhibitor of polyamine biosynthesis that inhibits ornithine decarboxylase, adenosylmethionine decarboxylase and spermidine synthase

R. M. Khomutov, Tapani Hyvönen, Eira Karvonen et al. · Biochemical and Biophysical Research Communications · 1985 · 47 citations

Biochemistry, Medicine, Spermidine Synthase +5

1-Aminooxy-3-aminopropane reversibly prevents the proliferation of cultured baby hamster kidney cells by interfering with polyamine synthesis.

Tapani Hyvönen, L. Alakuijala, L C Andersson et al. · Journal of Biological Chemistry · 1988 · 45 citations · Full text

Embryo Culture, New Drug, Mm Spermidine +12