Janel Lape

Integration of a CD19 CAR into the TCR Alpha Chain Locus Streamlines Production of Allogeneic Gene-Edited CAR T Cells

Daniel T. MacLeod, Jeyaraj Antony, Aaron J. Martin et al. · Molecular Therapy · 2017 · 268 citations · Full text

Genetics, T-regulatory Cell, Genetic Engineering +7

Male‐sterile maize plants produced by targeted mutagenesis of the cytochrome <scp>P</scp>450‐like gene (<i><scp>MS</scp>26</i>) using a re‐designed I–<i><scp>C</scp>re</i>I homing endonuclease

Vesna Djukanovic, Jeff Smith, Keith Lowe et al. · The Plant Journal · 2013 · 135 citations

Plant Genetics, Genetics, Molecular Biology +17

Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol

Lili Wang, Jeff Smith, Camilo Breton et al. · Nature Biotechnology · 2018 · 122 citations

Oxysterol, Liver Physiology, Meganuclease Targeting +7

Protein fabrication automation

J. Colin Cox, Janel Lape, Mahmood A. Sayed et al. · Protein Science · 2007 · 59 citations · Full text

Engineering, Rapid Writing, Molecular Biology +17

Targeting the hepatitis B cccDNA with a sequence-specific ARCUS nuclease to eliminate hepatitis B virus in vivo

Cassandra L. Gorsuch, Paige S. Nemec, Yu Mei et al. · Molecular Therapy · 2022 · 45 citations · Full text

Viral Replication, Hbv Cure, Immunology +18