Hellen Houlleberghs

Exonic Sequences Provide Better Targets for Antisense Oligonucleotides Than Splice Site Sequences in the Modulation of Duchenne Muscular Dystrophy Splicing

Annemieke Aartsma‐Rus, Hellen Houlleberghs, J.C.T. van Deutekom et al. · Oligonucleotides · 2010 · 40 citations

Life Sciences, Molecular Biology, Molecular Genetics +14

Oligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated <i>MSH2</i> DNA mismatch repair gene variants

Hellen Houlleberghs, Marleen Dekker, Hildo C. Lantermans et al. · Proceedings of the National Academy of Sciences · 2016 · 37 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights

Assia Merabet, Hellen Houlleberghs, Kate Maclagan et al. · Biochemical Journal · 2010 · 31 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

Suspected Lynch syndrome associated MSH6 variants: A functional assay to determine their pathogenicity

Hellen Houlleberghs, Anne Goverde, Jarnick Lusseveld et al. · PLoS Genetics · 2017 · 26 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding

Susanne R. Bruekner, Wietske Pieters, Alexander Fish et al. · Nucleic Acids Research · 2023 · 11 citations · Full text

Life Sciences, Genetics, Molecular Biology +15