David C. McKinney

Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy

Moran Dvela‐Levitt, Maria Kost‐Alimova, Maheswarareddy Emani et al. · Cell · 2019 · 191 citations · Full text

Protein Function, Autoimmune Disease, Medicine +9

Molecular basis for substrate recruitment to the PRMT5 methylosome

Kathleen M. Mulvaney, Christa Blomquist, Nischal Acharya et al. · Molecular Cell · 2021 · 83 citations · Full text

Chromatin, Medicine, Natural Sciences +9

Thiazolopyridine Ureas as Novel Antitubercular Agents Acting through Inhibition of DNA Gyrase B

Manoj Kale, Anandkumar Raichurkar, Shahul Hameed P et al. · Journal of Medicinal Chemistry · 2013 · 66 citations · Full text

Antiparasitic Agent, Molecular Biology, Antimicrobial Chemotherapy +21

Antibacterial FabH Inhibitors with Mode of Action Validated in <i>Haemophilus influenzae</i> by in Vitro Resistance Mutation Mapping

David C. McKinney, Charles J. Eyermann, Rong-Fang Gu et al. · ACS Infectious Diseases · 2016 · 59 citations

Action Validated, Escherichia Coli, Antimicrobial Chemotherapy +22

Selective Inhibitors of Bacterial t-RNA-(N¹G37) Methyltransferase (TrmD) That Demonstrate Novel Ordering of the Lid Domain

Pamela Hill, Ayome Abibi, Robert Albert et al. · Journal of Medicinal Chemistry · 2013 · 54 citations

Bioorganic Chemistry, Engineering, X-ray Cocrystal Structures +20