Thomas A. Pires

Development of Novel Quaternary Ammonium Linkers for Antibody–Drug Conjugates

Patrick Burke, Joseph Z. Hamilton, Thomas A. Pires et al. · Molecular Cancer Therapeutics · 2016 · 60 citations · Full text

Peptide Science, Pharmacotherapy, Immunotherapeutics +20

Substrate interactions guide cyclase engineering and lasso peptide diversification

Susanna E. Barrett, Yin Song, Peter Jordan et al. · Nature Chemical Biology · 2024 · 28 citations · Full text

Engineering, Biochemistry, Lasso Peptide Diversification +9

Glucuronide-Linked Antibody–Tubulysin Conjugates Display Activity in MDR+ and Heterogeneous Tumor Models

Patrick Burke, Joseph Z. Hamilton, Thomas A. Pires et al. · Molecular Cancer Therapeutics · 2018 · 21 citations

SGN-CD228A Is an Investigational CD228-Directed Antibody–Drug Conjugate with Potent Antitumor Activity across a Wide Spectrum of Preclinical Solid Tumor Models

Rebecca Mazahreh, Marsha L. Mason, John J. Gosink et al. · Molecular Cancer Therapeutics · 2023 · 21 citations · Full text

Immunology, Immunoediting, Wide Spectrum +18

Characteristics and risk factors for poor outcome in patients with systemic vasculitis involving the gastrointestinal tract

Ségolène Gendreau, Raphaël Porcher, Benjamin Thoreau et al. · Seminars in Arthritis and Rheumatism · 2021 · 16 citations · Full text

Rheumatology, Systemic Vasculitis, Clinical Finding +10