Jo Ann W. Byl

Voreloxin Is an Anticancer Quinolone Derivative that Intercalates DNA and Poisons Topoisomerase II

Rachael E. Hawtin, David E. Stockett, Jo Ann W. Byl et al. · PLoS ONE · 2010 · 149 citations · Full text

Medicine, Oncology, Pharmacology +14

First Ruthenium Organometallic Complex of Antibacterial Agent Ofloxacin. Crystal Structure and Interactions with DNA

Iztok Turel, Jakob Kljun, Franc Perdih et al. · Inorganic Chemistry · 2010 · 104 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17

Molecular analysis of t(15;17) genomic breakpoints in secondary acute promyelocytic leukemia arising after treatment of multiple sclerosis

Syed K. Hasan, Ashley N. Mays, Tiziana Ottone et al. · Blood · 2008 · 81 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

DNA Topoisomerase II as the Target for the Anticancer Drug TOP-53:  Mechanistic Basis for Drug Action

Jo Ann W. Byl, Susan D. Cline, Teruhiro Utsugi et al. · Biochemistry · 2000 · 81 citations

Medicine, Oncology, Pharmacology +15

Cobalt Enhances DNA Cleavage Mediated by Human Topoisomerase IIα <i>in Vitro</i> and in Cultured Cells

Erin L. Baldwin, Jo Ann W. Byl, Neil Osheroff · Biochemistry · 2003 · 79 citations

Life Sciences, Biochemistry, Molecular Biology +14