Ying Hsiu Liu

Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers

Manaswini Sivaramakrishnan, Kathleen McCarthy, Sébastien Campagne et al. · Nature Communications · 2017 · 219 citations · Full text

Motor neuron cell-nonautonomous rescue of spinal muscular atrophy phenotypes in mild and severe transgenic mouse models

Yimin Hua, Ying Hsiu Liu, Kentaro Sahashi et al. · Genes & Development · 2015 · 148 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis +14

RNA-sequencing of a mouse-model of spinal muscular atrophy reveals tissue-wide changes in splicing of U12-dependent introns

Thomas Koed Doktor, Yimin Hua, Henriette S. Andersen et al. · Nucleic Acids Research · 2016 · 104 citations · Full text

Tetracyclines That Promote <i>SMN2</i> Exon 7 Splicing as Therapeutics for Spinal Muscular Atrophy

Michelle L. Hastings, Joel Berniac, Ying Hsiu Liu et al. · Science Translational Medicine · 2009 · 84 citations

Neurodegenerative Diseases, Spinal Cord Injury, Smn2 Promoter Activation +10

Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy

Luciano E. Marasco, Gwendal Dujardin, Rui Sousa‐Luís et al. · Cell · 2022 · 71 citations · Full text

Chromatin, Spinal Cord Injury, Genome Surgery +10