Vered Klinghofer

ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models

Cherrie K. Donawho, Yan Luo, Yanping Luo et al. · Clinical Cancer Research · 2007 · 773 citations · Full text

Medicine, Oncology, Pharmacology +15

Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(<i>R</i>)-2-methylpyrrolidin-2-yl]-1<i>H</i>-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

Thomas D. Penning, Gui‐Dong Zhu, Viraj B. Gandhi et al. · Journal of Medicinal Chemistry · 2008 · 269 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Potent and selective inhibitors of Akt kinases slow the progress of tumors <i>in vivo</i>

Yan Luo, Alexander R. Shoemaker, Xuesong Liu et al. · Molecular Cancer Therapeutics · 2005 · 244 citations · Full text

Medicine, Oncology, Pharmacology +15

Novel potent and selective inhibitors of inducible nitric oxide synthase.

Masaki Nakane, Vered Klinghofer, Jane Kuk et al. · Molecular Pharmacology · 1995 · 127 citations

Life Sciences, Medicinal Chemistry, Pharmacology +6

Discovery of a Peptide-Based Renin Inhibitor with Oral Bioavailability and Efficacy

Hollis D. Kleinert, Saul H. Rosenberg, William R. Baker et al. · Science · 1992 · 108 citations

Pharmacy, Pharmacokinetics, Pharmacology +14