Integrin αvβ1 promotes infection by human metapneumovirus

G. Cseke, Melissa S. Maginnis, Reagan G. Cox, +5

Proceedings of the National Academy of Sciences

Human Metapneumovirus Fusion Protein Vaccines That Are Immunogenic and Protective in Cotton Rats

G. Cseke, David W. Wright, Sharon J. Tollefson, +3

Journal of Virology

A Recombinant Human Monoclonal Antibody to Human Metapneumovirus Fusion Protein That Neutralizes Virus In Vitro and Is Effective Therapeutically In Vivo

John V. Williams, Zhifeng Chen, G. Cseke, +10

Journal of Virology

Comparison of Orexin 1 and Orexin 2 Ligand Binding Modes Using X-ray Crystallography and Computational Analysis

Mathieu Rappas, A. Ali, K.A. Bennett, +15

Journal of Medicinal Chemistry

Monoclonal anti-β₁-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment

Catherine J. Hutchings, G. Cseke, Greg Osborne, +9

mAbs

Structure-Based Drug Discovery of <i>N</i> -(( <i>R</i> )-3-(7-Methyl-1 <i>H</i> -indazol-5-yl)-1-oxo-1-((( <i>S</i> )-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2′-oxo-1′,2′-dihydrospiro[piperidine-4,4′-pyrido[2,3- <i>d</i> ][1,3]oxazine]-1-carboxamide (HTL22562): A Calcitonin Gene-Related Peptide Receptor Antagonist for Acute Treatment of Migraine

S.J. Bucknell, Mark A. Ator, Alastair Brown, +13

Journal of Medicinal Chemistry

A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β1-adrenoceptors expressed in stable cell lines

Mark Soave, G. Cseke, Catherine J. Hutchings, +3

Biochemical Pharmacology