Toshimitsu Komatsu

Life Span Extension by Reduction in Growth Hormone-Insulin-Like Growth Factor-1 Axis in a Transgenic Rat Model

Isao Shimokawa, Yoshikazu Higami, Masanori Utsuyama et al. · American Journal Of Pathology · 2002 · 130 citations · Full text

Life Sciences, Endocrinology, Genetics +14

Lifespan extension by reduction of the growth hormone‐insulin‐like growth factor‐1 axis: relation to caloric restriction

Isao Shimokawa, Yoshikazu Higami, Tomoshi Tsuchiya et al. · The FASEB Journal · 2003 · 125 citations

Education, Endocrinology, Nutritional Sciences +14

The life‐extending effect of dietary restriction requires <scp>F</scp> oxo3 in mice

Isao Shimokawa, Toshimitsu Komatsu, Nobutaka Hayashi et al. · Aging Cell · 2015 · 108 citations · Full text

Medicine, Cancer Biology, Oncology +12

FoxO1 is involved in the antineoplastic effect of calorie restriction

Haruyoshi Yamaza, Toshimitsu Komatsu, Saori Wakita et al. · Aging Cell · 2010 · 95 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +16

Reduced FOXO1 Expression Accelerates Skin Wound Healing and Attenuates Scarring

Ryoichi Mori, Katsuya Tanaka, Maiko de Kerckhove et al. · American Journal Of Pathology · 2014 · 65 citations · Full text

Life Sciences, Dermatology, Molecular Biology +17