Wen-Yo Tu

Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy

Penelope J Boyd, Wen-Yo Tu, Hannah K. Shorrock et al. · PLoS Genetics · 2017 · 90 citations · Full text

Bioenergetic Status Modulates, Cellular Neurobiology, Disease Susceptibility +16

UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model

Kejing Zhang, Wang Ailian, Keke Zhong et al. · Neuron · 2021 · 48 citations · Full text

C9orf72 Animal Model, Protein Function, Molecular Physiology +6

Loss of mitochondrial protein CHCHD10 in skeletal muscle causes neuromuscular junction impairment

Yatao Xiao, Jianmin Zhang, Xiaoqiu Shu et al. · Human Molecular Genetics · 2019 · 46 citations

Muscle Function, Synaptic Transmission, Mitochondrial Chchd10 +17

Negative regulation of TREM2-mediated C9orf72 poly-GA clearance by the NLRP3 inflammasome

Xiaoqiu Shu, Wei Chen, Wen-Yo Tu et al. · Cell Reports · 2023 · 25 citations · Full text

Neurogenomics, Molecular Regulation, Immunology +28

Motoneurons innervation determines the distinct gene expressions in multinucleated myofibers

Lei Bai, Wen-Yo Tu, Yatao Xiao et al. · Cell & Bioscience · 2022 · 16 citations · Full text