Naresh Kumar Manchukonda

Rational Design, Synthesis, and Biological Evaluation of Third Generation α-Noscapine Analogues as Potent Tubulin Binding Anti-Cancer Agents

Naresh Kumar Manchukonda, Pradeep Kumar Naik, Seneha Santoshi et al. · PLoS ONE · 2013 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents

Seneha Santoshi, Naresh Kumar Manchukonda, Charu Suri et al. · Journal of Computer-Aided Molecular Design · 2014 · 39 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Copper(I) mediated facile synthesis of potent tubulin polymerization inhibitor, 9-amino-α-noscapine from natural α-noscapine

Naresh Kumar Manchukonda, Balasubramanian Sridhar, Pradeep Kumar Naik et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 27 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Structural investigations into the binding mode of a novel noscapine analogue, 9-(4-vinylphenyl) noscapine, with tubulin by biochemical analyses and molecular dynamic simulations

Tejashree Mahaddalkar, Pradeep Kumar Naik, Sinjan Choudhary et al. · Journal of Biomolecular Structure and Dynamics · 2016 · 26 citations

Life Sciences, Biochemistry, Molecular Biology +17

Synthesis and biological evaluation of novel biaryl type α-noscapine congeners

Naresh Kumar Manchukonda, Pradeep Kumar Naik, Balasubramanian Sridhar et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 22 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7