Metformin Downregulates the Insulin/IGF-I Signaling Pathway and Inhibits Different Uterine Serous Carcinoma (USC) Cells Proliferation and Migration in p53-Dependent or -Independent Manners

Rive Sarfstein, Yael Friedman, Zohar Attias-Geva, +3

PLoS ONE

Metformin InteractsChemoprevention StrategyPathologyCancer BiologyInsulin Signaling +15

Dual Role of Rac in the Assembly of NADPH Oxidase, Tethering to the Membrane and Activation of p67

Rive Sarfstein, Yara Gorzalczany, Ariel Mizrahi, +6

Journal of Biological Chemistry

Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1

Sharon Maor, Doris Mayer, Ronit I. Yarden, +4

Journal of Endocrinology

Insulin-like Growth Factor-I Receptor (IGF-IR) Translocates to Nucleus and Autoregulates IGF-IR Gene Expression in Breast Cancer Cells

Rive Sarfstein, Metsada Pasmanik‐Chor, Adva Yeheskel, +7

Journal of Biological Chemistry

Systems BiologySignal TransductionBreast OncologyInsulin-like Growth FactorGrowth Hormone +13

Characterization of two proteins from <i>Leishmania donovani</i> and their use for vaccination against visceral leishmaniasis.

Charles L. Jaffe, Nurit Rachamim, Rive Sarfstein

The Journal of Immunology

The intricate involvement of the Insulin-like growth factor receptor signaling in mild traumatic brain injury in mice

Vardit Rubovitch, Shahaf Edut, Rive Sarfstein, +2

Neurobiology of Disease

Traumatic Brain InjuryNeuroregenerationIntricate InvolvementBrain-immune InteractionNeuroprotection +7

Identification of thioredoxin-interacting protein (TXNIP) as a downstream target for IGF1 action

Karthik Nagaraj, Lena Lapkina-Gendler, Rive Sarfstein, +5

Proceedings of the National Academy of Sciences

The Mechanism of Action of the Histone Deacetylase Inhibitor Vorinostat Involves Interaction with the Insulin-Like Growth Factor Signaling Pathway

Rive Sarfstein, Ilan Bruchim, Ami Fishman, +1

PLoS ONE

Histone ModificationsGynecologyInsulin SignalingInsulin-like Growth FactorFibroblast Growth Factor +17

HMGA1 protein is a positive regulator of the insulin-like growth factor-I receptor gene

Aurora Aiello, Giuseppe Pandini, Rive Sarfstein, +4

European Journal of Cancer

Signal TransductionMolecular PhysiologySignaling PathwayG Protein-coupled ReceptorGrowth Hormone +8

p53 Regulates insulin-like growth factor-I receptor gene expression in uterine serous carcinoma and predicts responsiveness to an insulin-like growth factor-I receptor-directed targeted therapy

Zohar Attias-Geva, Itay Bentov, Dvora Kidron, +5

European Journal of Cancer

Tumor BiologyUterine Serous CarcinomaMedicineGynecologyPathology +6