Heparanase and Syndecan-1 Interplay Orchestrates Fibroblast Growth Factor-2-induced Epithelial-Mesenchymal Transition in Renal Tubular Cells

Valentina Masola, Giovanni Gambaro, Elena Tibaldi, +5

Journal of Biological Chemistry

UrologyRenal Tubular CellsEpithelial-mesenchymal InteractionsCell ProliferationFibroblast Growth Factor +9

NLRP3 Inflammasome Activation in Dialyzed Chronic Kidney Disease Patients

Simona Granata, Valentina Masola, Elisa Zoratti, +7

PLoS ONE

Healthy SubjectsMitochondrial DysfunctionRenal PathologyImmunologyRenal Inflammation +22

In vitro effects of interleukin (IL)-1 beta inhibition on the epithelial-to-mesenchymal transition (EMT) of renal tubular and hepatic stellate cells

Valentina Masola, Amedeo Carraro, Simona Granata, +8

Journal of Translational Medicine

Downregulation of Nuclear-Encoded Genes of Oxidative Metabolism in Dialyzed Chronic Kidney Disease Patients

Gianluigi Zaza, Simona Granata, Valentina Masola, +5

PLoS ONE

A new mechanism of action of sulodexide in diabetic nephropathy: inhibits heparanase-1 and prevents FGF-2-induced renal epithelial-mesenchymal transition

Valentina Masola, Maurizio Onisto, Gianluigi Zaza, +2

Journal of Translational Medicine

Heparanase is a key player in renal fibrosis by regulating TGF-β expression and activity

Valentina Masola, Gianluigi Zaza, Maria Francesca Secchi, +3

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Key PlayerFibrosisUrologyRenal PathologyTgf-β Expression +11

Glycosaminoglycans, proteoglycans and sulodexide and the endothelium: biological roles and pharmacological effects.

Valentina Masola, Gianluigi Zaza, Maurizio Onisto, +2

PubMed

Normal GlycocalyxGlycobiologyImmunologyCellular PhysiologyInflammation +14

Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury

Valentina Masola, Gianluigi Zaza, Giovanni Gambaro, +11

PLoS ONE

Heparanase regulates the M1 polarization of renal macrophages and their crosstalk with renal epithelial tubular cells after ischemia/reperfusion injury

Valentina Masola, Gianluigi Zaza, Gloria Bellin, +7

The FASEB Journal

Extracellular Matrix-Mediated Breast Cancer Cells Morphological Alterations, Invasiveness, and Microvesicles/Exosomes Release

Marco Franchi, Zoi Piperigkou, Konstantinos-Athanasios Karamanos, +2

Cells

Breast OncologyCollagen FibersCell AdhesionExtracellular MicrovesiclesBiomedical Engineering +17