Remco Merkx

Chemical Synthesis of Ubiquitin, Ubiquitin‐Based Probes, and Diubiquitin

Farid El Oualid, Remco Merkx, Reggy Ekkebus et al. · Angewandte Chemie International Edition · 2010 · 321 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +12

The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types

Alex C. Faesen, Mark P.A. Luna‐Vargas, Paul P. Geurink et al. · Chemistry & Biology · 2011 · 213 citations

Internal Regulatory Domains, Protein Function, Signal Transduction +13

A cascading activity-based probe sequentially targets E1–E2–E3 ubiquitin enzymes

Monique P. C. Mulder, Katharina F. Witting, Ilana Berlin et al. · Nature Chemical Biology · 2016 · 156 citations · Full text

Protein Function, Biochemistry, Natural Sciences +5

<i>N</i> -lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids

Robert S. Jansen, Ruben D. Addie, Remco Merkx et al. · Proceedings of the National Academy of Sciences · 2015 · 139 citations · Full text

Efficient microwave-assisted synthesis of multivalent dendrimeric peptides using cycloaddition reaction (click) chemistry

Dirk T. S. Rijkers, G. Wilma van Esse, Remco Merkx et al. · Chemical Communications · 2005 · 130 citations

Combinatorial Chemistry, Engineering, Efficient Microwave-assisted Synthesis +18