Lisa M. Gomez

Identification of a Region within the Cytoplasmic Domain of the Subtype B Vpu Protein of Human Immunodeficiency Virus Type 1 (HIV-1) That Is Responsible for Retention in the Golgi Complex and Its Absence in the Vpu Protein from a Subtype C HIV-1

Erik Pacyniak, Melissa Gomez, Lisa M. Gomez et al. · AIDS Research and Human Retroviruses · 2005 · 63 citations

Scrambling of the amino acids within the transmembrane domain of Vpu results in a simian-human immunodeficiency virus (SHIVTM) that is less pathogenic for pig-tailed macaques

David R. Hout, Melissa Gomez, Erik Pacyniak et al. · Virology · 2005 · 45 citations

Vpu Results, Virus Structure, Molecular Virology +10

A single amino acid substitution within the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein renders simian–human immunodeficiency virus (SHIVKU-1bMC33) susceptible to rimantadine

David R. Hout, Lisa M. Gomez, Erik Pacyniak et al. · Virology · 2006 · 38 citations

Virus Structure, Viral Replication, Human Retrovirus +11

Substitution of the transmembrane domain of Vpu in simian–human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques

David R. Hout, Melissa Gomez, Erik Pacyniak et al. · Virology · 2005 · 35 citations

Virus Structure, Molecular Virology, Medicine +13

Vpu-mediated CD4 down-regulation and degradation is conserved among highly divergent SIVcpz strains

Lisa M. Gomez, Erik Pacyniak, Melissa Flick et al. · Virology · 2005 · 25 citations

Vpu-mediated Cd4 Down-regulation, Natural Sciences, Pathogenesis +6