Jean M. Whaley

Discovery of Dapagliflozin: A Potent, Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for the Treatment of Type 2 Diabetes

Wei Meng, Bruce A. Ellsworth, Alexandra A. Nirschl et al. · Journal of Medicinal Chemistry · 2008 · 612 citations · Full text

Metabolic Syndrome, Diabetes Management, Biochemistry +10

SGLT2 Mediates Glucose Reabsorption in the Early Proximal Tubule

Volker Vallon, Kenneth A. Platt, Robyn Cunard et al. · Journal of the American Society of Nephrology · 2010 · 543 citations · Full text

Co-transporter Sglt2, Cellular Physiology, Renal Function +16

Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan

Berton Zbar, Takeshi Kishida, Fan Chen et al. · Human Mutation · 1996 · 502 citations

Genetics, Genetic Epidemiology, Pathology +22

The von Hippel-Lindau Tumor Suppressor Protein Is Required for Proper Assembly of an Extracellular Fibronectin Matrix

Michael Ohh, Robert L. Yauch, Kim M. Lonergan et al. · Molecular Cell · 1998 · 478 citations · Full text

Fibrosis, Medicine, Proper Assembly +11

Dapagliflozin, a Selective SGLT2 Inhibitor, Improves Glucose Homeostasis in Normal and Diabetic Rats

Song‐Ping Han, Deborah Hagan, Joseph R. Taylor et al. · Diabetes · 2008 · 416 citations · Full text