Sarah E. O’Connor

De novo production of the plant-derived alkaloid strictosidine in yeast

Stephanie Brown, Marc Clastre, Vincent Courdavault et al. · Proceedings of the National Academy of Sciences · 2015 · 454 citations · Full text

A microbial supply chain for production of the anti-cancer drug vinblastine

Jie Zhang, Lea G. Hansen, Olga Gudich et al. · Nature · 2022 · 411 citations · Full text

Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle

Lorenzo Caputi, Jakob Franke, Scott C. Farrow et al. · Science · 2018 · 376 citations

An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis

Fernando Geu‐Flores, Nathaniel H. Sherden, Vincent Courdavault et al. · Nature · 2012 · 328 citations

Biosynthesis, Engineering, Heterocyclic +8

Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

Frédéric H. Vaillancourt, Ellen Yeh, David A. Vosburg et al. · Nature · 2005 · 318 citations

Biosynthesis, Bioorganic Chemistry, Engineering +10