EndMT contributes to the onset and progression of cerebral cavernous malformations

Luigi Maddaluno, Noemi Rudini, Roberto Cuttano, +13

Nature

NeuroanatomyVascular MalformationCerebral Cavernous MalformationsNeurologyNeuroscience +3

Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo

Fabrizio Orsenigo, Costanza Giampietro, Aldo Ferrari, +12

Nature Communications

<scp>KLF</scp> 4 is a key determinant in the development and progression of cerebral cavernous malformations

Roberto Cuttano, Noemi Rudini, Luca Bravi, +12

EMBO Molecular Medicine

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

Maria Grazia Lampugnani, Fabrizio Orsenigo, Noemi Rudini, +4

Journal of Cell Science

InflammationSignal TransductionDevelopmental BiologySignaling PathwayCell Signaling +12

Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice

Gwénola Boulday, Noemi Rudini, Luigi Maddaluno, +7

The Journal of Experimental Medicine

Brain DevelopmentVascular MalformationCerebral Vascular RegulationAngiogenesisCraniofacial Development +14

Sulindac metabolites decrease cerebrovascular malformations in <i>CCM3</i> -knockout mice

Luca Bravi, Noemi Rudini, Roberto Cuttano, +9

Proceedings of the National Academy of Sciences

Wnt Activation of Immortalized Brain Endothelial Cells as a Tool for Generating a Standardized Model of the Blood Brain Barrier In Vitro

Roberta Paolinelli, Monica Corada, Luca Ferrarini, +10

PLoS ONE

The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells

Luigi Maddaluno, Sue Ellen Verbrugge, Chiara Martinoli, +6

The Journal of Experimental Medicine

Cell AdhesionImmunologyAdhesion Molecule L1DermatologyImmunotherapy +20

The adhesion molecule NCAM promotes ovarian cancer progression via FGFR signalling

Silvia Zecchini, Lorenzo Bombardelli, Alessandra Decio, +12

EMBO Molecular Medicine

Developmental BiologyGliomaAdhesion Molecule NcamMedicineCell Adhesion +13

Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization

Elena Magrini, Alessandra Villa, Francesca Angiolini, +13

Journal of Clinical Investigation

Endothelial CellsImmunologyPathologyCancer BiologyTumor Biology +16