Rafael A. Leos

Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction

Rafael A. Leos, Miranda J. Anderson, Xiaochuan Chen et al. · American Journal of Physiology-Endocrinology and Metabolism · 2010 · 96 citations

Intrauterine Growth Restriction, Gynecology, Norepinephrine Suppression +20

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302

Jonathan W. Wojtkowiak, Heather C Cornnell, Shingo Matsumoto et al. · Cancer & Metabolism · 2015 · 81 citations · Full text

A phase I trial of PX-12, a small-molecule inhibitor of thioredoxin-1, administered as a 72-hour infusion every 21 days in patients with advanced cancers refractory to standard therapy

Ramesh K. Ramanathan, Joe Stephenson, Glen J. Weiss et al. · Investigational New Drugs · 2011 · 40 citations

72-Hour Infusion, Oncology, Advanced Cancers +9

Evaluation of the “Steal” Phenomenon on the Efficacy of Hypoxia Activated Prodrug TH-302 in Pancreatic Cancer

Kate Bailey, Heather H. Cornnell, Arig Ibrahim‐Hashim et al. · PLoS ONE · 2014 · 31 citations · Full text

Tumor Biology, Tumor Hypoxia, Pancreatic Cancer +12

Radiosensitization of Hs-766T Pancreatic Tumor Xenografts in Mice Dosed with Dodecafluoropentane Nano-Emulsion–Preliminary Findings

Jennifer L. H. Johnson, Rafael A. Leos, Amanda F. Baker et al. · Journal of Biomedical Nanotechnology · 2014 · 30 citations · Full text