Benjamin J. Dugan

Depletion of Autoreactive Plasma Cells and Treatment of Lupus Nephritis in Mice Using CEP-33779, a Novel, Orally Active, Selective Inhibitor of JAK2

Lily Lu, Kristine L. Stump, Nate H. Wallace et al. · The Journal of Immunology · 2011 · 75 citations · Full text

Immunology, Immune Regulation, Biological Therapy +25

A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis

Kristine L. Stump, Lily Lu, Paweł Dobrzański et al. · Arthritis Research & Therapy · 2011 · 75 citations · Full text

A Selective, Orally Bioavailable 1,2,4-Triazolo[1,5-<i>a</i>]pyridine-Based Inhibitor of Janus Kinase 2 for Use in Anticancer Therapy: Discovery of CEP-33779

Benjamin J. Dugan, Diane E. Gingrich, Eugen F. Mesaros et al. · Journal of Medicinal Chemistry · 2012 · 62 citations · Full text

Novel 2,3,4,5-tetrahydro-benzo[d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models

Eugen F. Mesaros, Jason P. Burke, Jonathan D. Parrish et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 34 citations · Full text

Medicinal Chemistry, Pharmacological Study, Bioavailable Alk Inhibitors +11