Mannose impairs tumour growth and enhances chemotherapy

Pablo Sierra Gonzalez, James O’Prey, Simone Cardaci, +20

Nature

Tumor BiologyMannose ImpairsMalignant DiseaseMedicinePathology +5

Loss of autophagy causes a synthetic lethal deficiency in DNA repair

Emma Y. Liu, Naihan Xu, Jim O’Prey, +12

Proceedings of the National Academy of Sciences

MitophagyDna DamageAutophagy DeficiencyGeneticsApoptosis +15

The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCδ and proteasome-dependent regulation of Mcl-1 expression

Alice D. Baudot, P Jeandel, Xavier Mouska, +6

Oncogene

Signal TransductionCell RegulationReceptor Tyrosine KinaseAutophagyImmunology +9

DRAM-1 encodes multiple isoforms that regulate autophagy

Li Yen Mah, Jim O’Prey, Alice D. Baudot, +2

Autophagy

MitophagyCell DeathCellular PhysiologyTumor BiologyAutophagy Downstream +14

Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

Valentin J.A. Barthet, Martina Brucoli, Marcus J.G.W. Ladds, +11

Science Advances

Application of CRISPR/Cas9 to Autophagy Research

Jim O’Prey, Jun-Ichi Sakamaki, Alice D. Baudot, +5

Methods in enzymology on CD-ROM/Methods in enzymology

Cell AutophagyAutophagyGenetic EngineeringAutophagy ResearchGene Editing +4

3BP2 Adapter Protein Is Required for Receptor Activator of NFκB Ligand (RANKL)-induced Osteoclast Differentiation of RAW264.7 Cells

Amel Guezguez, Virginie Prod’homme, Xavier Mouska, +4

Journal of Biological Chemistry

SclerostinRaw264.7 CellsImmunologyCellular PhysiologyWild Type 3Bp2 +16

p53 directly regulates the glycosidase FUCA1 to promote chemotherapy-induced cell death

Alice D. Baudot, Diane Crighton, Jim O’Prey, +3

Cell Cycle

ApoptosisImmunologyCell DeathCancer BiologyCell Death Mechanisms +17

Cell-Penetrating TAT-FOXO3 Fusion Proteins Induce Apoptotic Cell Death in Leukemic Cells

Makram Essafi, Alice D. Baudot, Xavier Mouska, +3

Molecular Cancer Therapeutics

ApoptosisImmunologyCell DeathCell CycleCancer Biology +15

Using enhanced-mitophagy to measure autophagic flux

Alice D. Baudot, Martina Haller, Michaela Mrschtik, +2

Methods