The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCδ and proteasome-dependent regulation of Mcl-1 expression

Alice D. Baudot, P Jeandel, Xavier Mouska, +6

Oncogene

Signal TransductionCell RegulationReceptor Tyrosine KinaseAutophagyImmunology +9

Postnatal Soluble FGFR3 Therapy Rescues Achondroplasia Symptoms and Restores Bone Growth in Mice

Stephanie García, Béatrice Dirat, Thomas Tognacci, +9

Science Translational Medicine

Regenerative MedicineSclerostinDevelopmental BiologyShort StatureBone Morphogenic Protein +13

Subchronic Glucocorticoid Receptor Inhibition Rescues Early Episodic Memory and Synaptic Plasticity Deficits in a Mouse Model of Alzheimer’s Disease

Fabien Lanté, Magda Chafaï, Elisabeth Raymond, +6

Neuropsychopharmacology

Synaptic PlasticitySynaptic Plasticity DeficitsAlzheimer's DiseaseBrain FunctionSynaptic Neuroscience +11

Mesopontine cholinergic inputs to midbrain dopamine neurons drive stress-induced depressive-like behaviors

Sebastián P. Fernández, Loïc Broussot, Fabio Marti, +6

Nature Communications

NeurotransmitterAffective NeuroscienceDopamine NeuronsPsychologySocial Sciences +19

Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein

Paula A. Pousinha, Xavier Mouska, Elisabeth Raymond, +9

eLife

Synaptic Glun2b-nmda ReceptorsSynaptic TransmissionNeurotransmitterNeurochemical BiomarkersNeurotransmission +17

The Amyloid Precursor Protein C-Terminal Domain Alters CA1 Neuron Firing, Modifying Hippocampus Oscillations and Impairing Spatial Memory Encoding

Paula A. Pousinha, Xavier Mouska, Daniela Bianchi, +13

Cell Reports

3BP2 Adapter Protein Is Required for Receptor Activator of NFκB Ligand (RANKL)-induced Osteoclast Differentiation of RAW264.7 Cells

Amel Guezguez, Virginie Prod’homme, Xavier Mouska, +4

Journal of Biological Chemistry

SclerostinRaw264.7 CellsImmunologyCellular PhysiologyWild Type 3Bp2 +16

Cherubism allele heterozygosity amplifies microbe-induced inflammatory responses in murine macrophages

Virginie Prod’homme, Laurent Boyer, Nicholas Dubois, +7

Journal of Clinical Investigation

Macrophage ActivationInnate Immune SystemImmunologyImmune RegulationInnate Immunity +21

Cell-Penetrating TAT-FOXO3 Fusion Proteins Induce Apoptotic Cell Death in Leukemic Cells

Makram Essafi, Alice D. Baudot, Xavier Mouska, +3

Molecular Cancer Therapeutics

ApoptosisImmunologyCell DeathCell CycleCancer Biology +15

Combination of blood and biphasic calcium phosphate microparticles for the reconstruction of large bone defects in dog: A pilot study

Thierry Balaguer, Borhane H. Fellah, Florian Boukhechba, +10

Journal of Biomedical Materials Research Part A