Donald Tweedie

THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE

Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf et al. · Drug Metabolism and Disposition · 2003 · 784 citations

Medicine, Pharmacokinetics, Pharmacology +17

The Conduct of In Vitro and In Vivo Drug‐Drug Interaction Studies: A PhRMA Perspective

Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf et al. · The Journal of Clinical Pharmacology · 2003 · 309 citations

Medicine, Pharmacokinetics, Pharmacology +17

Meeting the Challenge of Predicting Hepatic Clearance of Compounds Slowly Metabolized by Cytochrome P450 Using a Novel Hepatocyte Model, HepatoPac

Tom S. Chan, Hongbin Yu, Amanda Moore et al. · Drug Metabolism and Disposition · 2013 · 149 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Identification of the major human liver cytochrome P450 isoform(s) responsible for the formation of the primary metabolites of ziprasidone and prediction of possible drug interactions

Chandra Prakash, Amin Kamel, Donghui Cui et al. · British Journal of Clinical Pharmacology · 2000 · 123 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Induction of microsomal NADPH-cytochrome P-450 reductase and cytochrome P-450IVA1 (P-450LA omega) by dehydroepiandrosterone in rats: a possible peroxisomal proliferator.

H Q Wu, J Masset-Brown, Donald Tweedie et al. · PubMed · 1989 · 87 citations

Life Sciences, Pharmacology, Toxicology +17