Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch

Wen Juan Tu, Robert McCuaig, Abel Tan, +14

Frontiers in Immunology

Role of CD44⁺Stem Cells in Mural Cell Formation in the Human Choroid: Evidence of Vascular Instability Due to Limited Pericyte Ensheathment

Tailoi Chan‐Ling, Mark E. Koina, Janet R. McColm, +5

Investigative Ophthalmology & Visual Science

The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon

Dessislava Mladenova, Joseph J. Daniel, Jane E. Dahlstrom, +6

Gut

Nuclear-Biased DUSP6 Expression is Associated with Cancer Spreading Including Brain Metastasis in Triple-Negative Breast Cancer

Fan Wu, Robert McCuaig, Christopher R. Sutton, +10

International Journal of Molecular Sciences

Breast OncologyMedicineNuclear Dusp6Brain MetastasisPathology +11

Effects of bacterial products on enterocyte–macrophage interactions in vitro

Peter Tyrer, Elaine Bean, A. Ruth Foxwell, +1

Biochemical and Biophysical Research Communications

Bacterial ProductsMicrobial DiseaseAntibioticsMicrobial PathogensMedicine +6

HIF1α deficiency reduces colon inflammation in a mouse model of proximal colon cancer

Dessislava Mladenova, Jane E. Dahlstrom, Phuong Tran, +6

Disease Models & Mechanisms

Evidence of hematopoietic differentiation, vasculogenesis and angiogenesis in the formation of human choroidal blood vessels

Tailoi Chan‐Ling, Jane E. Dahlstrom, Mark E. Koina, +6

Experimental Eye Research

Vascular DiseaseDevelopmental BiologyAngiogenesisOphthalmologyMedicine +8

Immunohistochemical expression of EGFR in colorectal carcinoma correlates with high but not low level gene amplification, as demonstrated by CISH

Chris Hemmings, Amy Broomfield, Elaine Bean, +2

Pathology

Tumor BiologyMedicinePathologyColorectal CancerColorectal Carcinoma Correlates +6

Mouse Model of Mutated in Colorectal Cancer Gene Deletion Reveals Novel Pathways in Inflammation and Cancer

Nicola Currey, Zeenat Jahan, C. Elizabeth Caldon, +14

Cellular and Molecular Gastroenterology and Hepatology

Selective Targeting of Protein Kinase C (PKC)-θ Nuclear Translocation Reduces Mesenchymal Gene Signatures and Reinvigorates Dysfunctional CD8+ T Cells in Immunotherapy-Resistant and Metastatic Cancers

Jenny C. Dunn, Robert McCuaig, Abel Tan, +22

Cancers