Anitha Shanmugham

Mechanism of USP7/HAUSP Activation by Its C-Terminal Ubiquitin-like Domain and Allosteric Regulation by GMP-Synthetase

Alex C. Faesen, Annette M.G. Dirac, Anitha Shanmugham et al. · Molecular Cell · 2011 · 248 citations · Full text

Protein Function, Signal Transduction, Protein Expression +11

Nonhydrolyzable Ubiquitin−Isopeptide Isosteres as Deubiquitinating Enzyme Probes.

Anitha Shanmugham, Alexander Fish, Mark P.A. Luna‐Vargas et al. · Journal of the American Chemical Society · 2010 · 74 citations

Substrate Selectivity, Protein Assembly, Molecular Biology +18

Membrane Binding of Twin Arginine Preproteins as an Early Step in Translocation

Anitha Shanmugham, Harro W. Wong Fong Sang, Yves J. M. Bollen et al. · Biochemistry · 2006 · 63 citations

Proteinlipid Interaction, Protein Secretion, Protein Assembly +17

Catechol Pyrazolinones as Trypanocidals: Fragment-Based Design, Synthesis, and Pharmacological Evaluation of Nanomolar Inhibitors of Trypanosomal Phosphodiesterase B1

Kristina M. Orrling, Chimed Jansen, Xuan Lan Vu et al. · Journal of Medicinal Chemistry · 2012 · 55 citations · Full text

DUBs and disease: activity assays for inhibitor development.

Anitha Shanmugham, Huib Ovaa · PubMed · 2008 · 32 citations

Inhibitory Activity, Protein Function, Biochemistry +13