Andreas Rascher

Cloning and characterization of a gene cluster for geldanamycin production in<i>Streptomyces hygroscopicus</i>NRRL 3602

Andreas Rascher, Zhihao Hu, N. Viswanathan et al. · FEMS Microbiology Letters · 2003 · 149 citations · Full text

Biology, Polyketide Synthase Genes, Biosynthesis +14

Engineered Biosynthesis of Geldanamycin Analogs for Hsp90 Inhibition

Kedar G. Patel, Misty Piagentini, Andreas Rascher et al. · Chemistry & Biology · 2004 · 130 citations · Full text

Biosynthesis, Engineering, Medicine +7

Insights into the Biosynthesis of the Benzoquinone Ansamycins Geldanamycin and Herbimycin, Obtained by Gene Sequencing and Disruption

Andreas Rascher, Zhihao Hu, Greg O. Buchanan et al. · Applied and Environmental Microbiology · 2005 · 96 citations · Full text

Rapid Engineering of the Geldanamycin Biosynthesis Pathway by Red/ET Recombination and Gene Complementation

Leandro Vetcher, Zong‐Qiang Tian, Robert McDaniel et al. · Applied and Environmental Microbiology · 2005 · 28 citations · Full text

Production of 8-Demethylgeldanamycin and 4,5-Epoxy-8-demethylgeldanamycin from a Recombinant Strain of <i>Streptomyces </i><i>h</i><i>ygroscopicus</i>

Greg O. Buchanan, Rika Regentin, Misty Piagentini et al. · Journal of Natural Products · 2005 · 19 citations

Authentic Geldanamycin Derivatives, Industrial Mycology, Medicinal Chemistry +13