Chin Fung Kelvin Kan

Arachidonic acid downregulates acyl-CoA synthetase 4 expression by promoting its ubiquitination and proteasomal degradation

Chin Fung Kelvin Kan, Amar Singh, Diana M. Stafforini et al. · Journal of Lipid Research · 2014 · 70 citations · Full text

Acsl4 Protein, Acsl4 Protein Expression, Apoptosis +23

Reduction of circulating PCSK9 and LDL-C levels by liver-specific knockdown of HNF1α in normolipidemic mice

Vikram R. Shende, Minhao Wu, Amar Singh et al. · Journal of Lipid Research · 2015 · 61 citations · Full text

High-fructose diet downregulates long-chain acyl-CoA synthetase 3 expression in liver of hamsters via impairing LXR/RXR signaling pathway

Bin Dong, Chin Fung Kelvin Kan, Amar Singh et al. · Journal of Lipid Research · 2013 · 45 citations · Full text

Liver-specific knockdown of long-chain acyl-CoA synthetase 4 reveals its key role in VLDL-TG metabolism and phospholipid synthesis in mice fed a high-fat diet

Amar Singh, Chin Fung Kelvin Kan, Fredric B. Kraemer et al. · American Journal of Physiology-Endocrinology and Metabolism · 2019 · 40 citations · Full text

High-fat Diet, Fatty Liver Disease, Glucose Tolerance +17

SREBP2 Activation Induces Hepatic Long-chain Acyl-CoA Synthetase 1 (ACSL1) Expression in Vivo and in Vitro through a Sterol Regulatory Element (SRE) Motif of the ACSL1 C-promoter

Amar Singh, Chin Fung Kelvin Kan, Bin Dong et al. · Journal of Biological Chemistry · 2016 · 39 citations · Full text