Alexandre E. Escargueil

The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane

Alexia Garrigues, Alexandre E. Escargueil, Stéphane Orlowski · Proceedings of the National Academy of Sciences · 2002 · 202 citations · Full text

Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743

Daniele G. Soares, Alexandre E. Escargueil, Virginie Poindessous et al. · Proceedings of the National Academy of Sciences · 2007 · 149 citations

Dna Damage, Apoptosis, Immunology +16

Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation

Rebecca H. Chisholm, Tommaso Lorenzi, Alexander Lorz et al. · Cancer Research · 2015 · 141 citations

Modeling the Effects of Space Structure and Combination Therapies on Phenotypic Heterogeneity and Drug Resistance in Solid Tumors

Alexander Lorz, Tommaso Lorenzi, Jean Clairambault et al. · Bulletin of Mathematical Biology · 2014 · 116 citations · Full text

Tumor Biology, Health Sciences, Tumor Heterogeneity +13

Trabectedin and Its C Subunit Modified Analogue PM01183 Attenuate Nucleotide Excision Repair and Show Activity toward Platinum-Resistant Cells

Daniele G. Soares, Miriana S. Machado, Céline J. Rocca et al. · Molecular Cancer Therapeutics · 2011 · 77 citations

Tumor Biology, Genome Instability, Show Activity +13