Ing-Kae Wang

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

Xiayang Qiu, Anil Mistry, Mark Ammirati et al. · Nature Structural & Molecular Biology · 2007 · 270 citations

Crystal Structure, Proteinlipid Interaction, Long Tunnel +7

Pharmacologic Inhibition of Site 1 Protease Activity Inhibits Sterol Regulatory Element-Binding Protein Processing and Reduces Lipogenic Enzyme Gene Expression and Lipid Synthesis in Cultured Cells and Experimental Animals

Julie L. Hawkins, Michael Robbins, Laurie C. Warren et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 146 citations

Anilinoquinazoline Inhibitors of Fructose 1,6-Bisphosphatase Bind at a Novel Allosteric Site:  Synthesis, In Vitro Characterization, and X-ray Crystallography

Stephen W. Wright, Anthony Carlo, Maynard D. Carty et al. · Journal of Medicinal Chemistry · 2002 · 81 citations · Full text

Drug Target, Bioorganic Chemistry, Novel Allosteric Site +19

Suppression of Invasion and MMP-9 Expression in NIH 3T3 and v-H-Ras 3T3 Fibroblasts by Lovastatin through Inhibition of Ras Isoprenylation

Ing-Kae Wang, Shoei‐Yn Lin‐Shiau, Jen‐Kun Lin · Oncology · 2000 · 70 citations

Induction of Apoptosis by Lovastatin through Activation of Caspase-3 and DNase II in Leukaemia HL-60 Cells

Ing-Kae Wang, Shoei‐Yn Lin‐Shiau, Jen‐Kun Lin · Pharmacology & Toxicology · 2000 · 57 citations

Lipid Peroxidation, Apoptosis, Immunology +16