Patrik Nygren

Lecanemab, Aducanumab, and Gantenerumab — Binding Profiles to Different Forms of Amyloid-Beta Might Explain Efficacy and Side Effects in Clinical Trials for Alzheimer's Disease

Linda Söderberg, Malin Johannesson, Patrik Nygren et al. · Neurotherapeutics · 2022 · 413 citations · Full text

Life Sciences, Pharmacology, Dementia +15

Affinity of talin-1 for the β3-integrin cytosolic domain is modulated by its phospholipid bilayer environment

David T. Moore, Patrik Nygren, Hyunil Jo et al. · Proceedings of the National Academy of Sciences · 2011 · 66 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: A mechanism likely deranged in Hereditary Multiple Exostoses

Julianne Huegel, Christina Mundy, Federica Sgariglia et al. · Developmental Biology · 2013 · 65 citations

Medicine, Genetics, Molecular Biology +17

Induction of Structure and Function in a Designed Peptide upon Adsorption on a Silica Nanoparticle

Martin Lundqvist, Patrik Nygren, Bengt‐Harald Jonsson et al. · Angewandte Chemie International Edition · 2006 · 57 citations

Natural Sciences, Biochemistry, Materials Science +14

ABBV-0805, a novel antibody selective for soluble aggregated α-synuclein, prolongs lifespan and prevents buildup of α-synuclein pathology in mouse models of Parkinson's disease

Eva Nordström, Fredrik Eriksson, Jessica Sigvardson et al. · Neurobiology of Disease · 2021 · 54 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17