A transfer-RNA-derived small RNA regulates ribosome biogenesis

Hak Kyun Kim, Gabriele Fuchs, Shengchun Wang, +13

Nature

Rna BiologySmall RnaRna TransportGene ExpressionMedicine +3

Biological basis for restriction of microRNA targets to the 3′ untranslated region in mammalian mRNAs

Shuo Gu, Lan Jin, Feijie Zhang, +2

Nature Structural & Molecular Biology

EngineeringUntranslated RegionMammalian MrnasGeneticsRna Biology +7

A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo

Jun Chu, Young‐Hee Oh, Alex Sens, +18

Nature Biotechnology

Fluorescence MicroscopyDual-emission MicroscopyEngineeringNovel Imaging MethodBiomedical Imaging +7

The Loop Position of shRNAs and Pre-miRNAs Is Critical for the Accuracy of Dicer Processing In Vivo

Shuo Gu, Lan Jin, Yue Zhang, +4

Cell

Systems BiologyEngineeringDicer ProcessingRna BiologyPre-mirnas Is Critical +8

Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals

Yichi Su, Joel R. Walker, Yun‐Hee Park, +16

Nature Methods

EngineeringBioluminescenceBiomedical ImagingBiophotonicsBiomedical Engineering +3

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity

Nicole K. Paulk, Katja Pekrun, Erhua Zhu, +17

Molecular Therapy

Diesel Exhaust Particle-Exposed Human Bronchial Epithelial Cells Induce Dendritic Cell Maturation and Polarization via Thymic Stromal Lymphopoietin

Bertram Bleck, Doris B. Tse, Maria A. Curotto de Lafaille, +2

Journal of Clinical Immunology

InflammationLung DepositionInflammatory Lung DiseaseLung InflammationImmunology +5

Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors

Katja Pekrun, Gustavo de Alencastro, Qing-Jun Luo, +11

JCI Insight

ImmunologyMolecular BiologyGene DeliveryRegenerative MedicineTranslational Medicine +17

Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes

Shuo Gu, Lan Jin, Feijie Zhang, +4

Proceedings of the National Academy of Sciences

Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain

Shuo Gu, Lan Jin, Yong Huang, +2

Current Biology

Signal TransductionSignaling PathwayMolecular RegulationMedicineSignal Recognition +3