Lu Gan

CYP3A-like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells.

Lu Gan, M. Arthur Moseley, B. Khosla et al. · Drug Metabolism and Disposition · 1996 · 145 citations

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Non–Bile Acid FXR Agonist Tropifexor (LJN452) in Healthy Volunteers

Michael K. Badman, Jin Chen, Sachin N. Desai et al. · Clinical Pharmacology in Drug Development · 2019 · 70 citations · Full text

Obesity, Metabolic Syndrome, Hepatology +15

Role of NADPH-Cytochrome P450 Reductase and Cytochrome-b5/NADH-b5 Reductase in Variability of CYP3A Activity in Human Liver Microsomes

Lu Gan, Lisa L. von Moltke, Lauren A. Trepanier et al. · Drug Metabolism and Disposition · 2008 · 44 citations

A phase 1b trial of the CXCR4 inhibitor mavorixafor and nivolumab in advanced renal cell carcinoma patients with no prior response to nivolumab monotherapy

Toni K. Choueiri, Michael B. Atkins, Tracy L. Rose et al. · Investigational New Drugs · 2021 · 39 citations · Full text

N6‐methyladenosine reader YTHDF3 regulates melanoma metastasis via its ‘executor' LOXL3

Haoze Shi, Jingshu Xiong, Lu Gan et al. · Clinical and Translational Medicine · 2022 · 34 citations · Full text