Jin Chen

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Non–Bile Acid FXR Agonist Tropifexor (LJN452) in Healthy Volunteers

Michael K. Badman, Jin Chen, Sachin N. Desai et al. · Clinical Pharmacology in Drug Development · 2019 · 71 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +13

Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism

Jin Chen, Bingtian Liang, Dongxue Bian et al. · Biochemical and Biophysical Research Communications · 2019 · 47 citations

Medicine, Biochemistry, Immunology +15

Ratio of Conjugated Chenodeoxycholic to Muricholic Acids is Associated with Severity of Nonalcoholic Steatohepatitis

Jin Chen, Ming‐Hua Zheng, Jun Liu et al. · Obesity · 2019 · 45 citations

Medicine, Biochemistry, Pharmacology +17

Edaravone dexborneol ameliorates cognitive impairment by regulating the NF-κB pathway through AHR and promoting microglial polarization towards the M2 phenotype in mice with bilateral carotid artery stenosis (BCAS)

Lei Li, Guojun He, Mingyu Shi et al. · European Journal of Pharmacology · 2023 · 31 citations

Life Sciences, Neuroscience, Pharmacology +15

ELANE enhances KEAP1 protein stability and reduces NRF2-mediated ferroptosis inhibition in metabolic dysfunction-associated fatty liver disease

Qingqing Yang, Xuan Shen, Yan Luo et al. · Cell Death and Disease · 2025 · 19 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17