Jin Chen

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Non–Bile Acid FXR Agonist Tropifexor (LJN452) in Healthy Volunteers

Michael K. Badman, Jin Chen, Sachin N. Desai et al. · Clinical Pharmacology in Drug Development · 2019 · 70 citations · Full text

Obesity, Metabolic Syndrome, Hepatology +15

Knockout of neutrophil elastase protects against western diet induced nonalcoholic steatohepatitis in mice by regulating hepatic ceramides metabolism

Jin Chen, Bingtian Liang, Dongxue Bian et al. · Biochemical and Biophysical Research Communications · 2019 · 45 citations

Inflammation, Hepatic Ceramides Metabolism, Metabolic Associated Steatohepatitis +13

Ratio of Conjugated Chenodeoxycholic to Muricholic Acids is Associated with Severity of Nonalcoholic Steatohepatitis

Jin Chen, Ming‐Hua Zheng, Jun Liu et al. · Obesity · 2019 · 44 citations

Edaravone dexborneol ameliorates cognitive impairment by regulating the NF-κB pathway through AHR and promoting microglial polarization towards the M2 phenotype in mice with bilateral carotid artery stenosis (BCAS)

Lei Li, Guojun He, Mingyu Shi et al. · European Journal of Pharmacology · 2023 · 29 citations

Microglial Polarization, M2 Phenotype, Alzheimer's Disease +14

Collagen triple helix repeat containing-1 exerts antifibrotic effects on human skin fibroblast and bleomycin-induced dermal fibrosis models

Zhu Shen, Tangfeng Su, Jin Chen et al. · Annals of Translational Medicine · 2021 · 13 citations · Full text