Jing Chai

Cell-Based Selection Expands the Utility of DNA-Encoded Small-Molecule Library Technology to Cell Surface Drug Targets: Identification of Novel Antagonists of the NK3 Tachykinin Receptor

Zining Wu, Todd L. Graybill, Xin Zeng et al. · ACS Combinatorial Science · 2015 · 133 citations

Drug Target, Immunology, Molecular Biology +20

The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors

Edgar R. Wood, Randy K. Bledsoe, Jing Chai et al. · Journal of Biological Chemistry · 2015 · 79 citations · Full text

Negative Regulator, Autoimmune Disease, Allergy +10

Development and Synthesis of DNA-Encoded Benzimidazole Library

Yun Ding, Jing Chai, Paolo A. Centrella et al. · ACS Combinatorial Science · 2018 · 52 citations

Combinatorial Chemistry, Targeted Library, Medicinal Chemistry +15

Discovery and Optimization of Potent, Selective, and <i>in Vivo</i> Efficacious 2-Aryl Benzimidazole BCATm Inhibitors

Hongfeng Deng, Jingye Zhou, Flora S. Sundersingh et al. · ACS Medicinal Chemistry Letters · 2016 · 44 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Drug Target +15

Asymmetric synthesis of α-amino aldehydes from sulfinimine (N-sulfinyl imine)-derived α-amino 1,3-dithianes. Formal synthesis of (−)-2,3-trans-3,4-cis-dihydroxyproline

Franklin A. Davis, Tokala Ramachandar, Jing Chai et al. · Tetrahedron Letters · 2006 · 32 citations

α-Amino Aldehydes, N-sulfinyl Imine, Engineering +10