Peter J. McHugh

Defining the Roles of Nucleotide Excision Repair and Recombination in the Repair of DNA Interstrand Cross-Links in Mammalian Cells

Inusha U. De Silva, Peter J. McHugh, Peter H. Clingen et al. · Molecular and Cellular Biology · 2000 · 441 citations

Life Sciences, Genetics, Molecular Biology +17

Phase I Study of the Poly(ADP-Ribose) Polymerase Inhibitor, AG014699, in Combination with Temozolomide in Patients with Advanced Solid Tumors

Ruth Plummer, Christopher J. Jones, Mark R. Middleton et al. · Clinical Cancer Research · 2008 · 384 citations · Full text

Medicine, Oncology, Pharmacology +15

Neuronal enhancers are hotspots for DNA single-strand break repair

Wei Wu, Sarah E. Hill, William J. Nathan et al. · Nature · 2021 · 235 citations · Full text

Life Sciences, Genetics, Neuroscience +10

A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1

Erkin Erdal, Syed Haider, Jan Rehwinkel et al. · Genes & Development · 2017 · 218 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation

George E. Ronson, Ann Liza Piberger, Martin R. Higgs et al. · Nature Communications · 2018 · 217 citations · Full text

Life Sciences, Genetics, Molecular Biology +17