Chantal A. Mutsaers

Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

Thomas M. Wishart, Chantal A. Mutsaers, Michell M. Reimer et al. · Journal of Clinical Investigation · 2014 · 175 citations · Full text

Molecular Regulation, Synaptic Signaling, Cellular Physiology +22

Properdin Binds to Late Apoptotic and Necrotic Cells Independently of C3b and Regulates Alternative Pathway Complement Activation

Wei Xu, Stefan P. Berger, Leendert A. Trouw et al. · The Journal of Immunology · 2008 · 136 citations

SMN deficiency disrupts brain development in a mouse model of severe spinal muscular atrophy

Thomas M. Wishart, Jack P.-W. Huang, Lyndsay M. Murray et al. · Human Molecular Genetics · 2010 · 135 citations · Full text

Brain Development, Neurological Disorder, Cell Proliferation +19

Reversible molecular pathology of skeletal muscle in spinal muscular atrophy

Chantal A. Mutsaers, Thomas M. Wishart, Douglas J. Lamont et al. · Human Molecular Genetics · 2011 · 98 citations · Full text

Muscle Function, Motor Neuron Disease, Genetics +20

PTEN Depletion Decreases Disease Severity and Modestly Prolongs Survival in a Mouse Model of Spinal Muscular Atrophy

Daniel Little, Chiara F. Valori, Chantal A. Mutsaers et al. · Molecular Therapy · 2014 · 52 citations · Full text