Concepedia

Author

Daniel Little

MRC Laboratory for Molecular Cell BiologyORCID

Also Known As

Cheryl Hemingway, D. V. Little, Daniel Little, Little, D

31

Publications

2.2K

Citations

14

H-Index

39

Concepts

All Affiliations

MRC Laboratory for Molecular Cell BiologyUniversity College LondonNational Hospital for Neurology and NeurosurgeryMRC Centre for Regenerative MedicineGreat Ormond Street Hospital
DL

About

Daniel Little is an author at MRC Laboratory for Molecular Cell Biology specializing in engineering, medicine, and regenerative medicine.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Engineering

5

5

220

2

Medicine

3

3

80

3

Biomedical Engineering

2

2

43

4

Biomolecular Engineering

2

2

128

5

Natural Sciences

1

1

28

Daniel Little

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13

Publications

2.1K

Citations

13

H-Index

YearCitations

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

Marthe H. R. Ludtmann, Plamena R. Angelova, Mathew H. Horrocks,

Nature Communications

2018

490

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

Emma Deas, Nunilo Cremades, Plamena R. Angelova,

Antioxidants and Redox Signaling

2015

352

α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production

Sébastien Paillusson, Patricia Gómez‐Suaga, Radu Stoica,

Acta Neuropathologica

2017

348

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Plamena R. Angelova, Minee L. Choi, Alexey V. Berezhnov,

Cell Death and Differentiation

2020

284

Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity

Minee L. Choi, Alexandre Chappard, Bhanu Singh,

Nature Neuroscience

2022

225

Encapsulation of Biomacromolecules within Polymersomes by Electroporation

Linge Wang, Luca Chierico, Daniel Little,

Angewandte Chemie International Edition

2012

114

A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA

Daniel Little, Christin Luft, Olukunbi Mosaku,

Scientific Reports

2018

65

PTEN Depletion Decreases Disease Severity and Modestly Prolongs Survival in a Mouse Model of Spinal Muscular Atrophy

Daniel Little, Chiara F. Valori, Chantal A. Mutsaers,

Molecular Therapy

2014

52

Agrobacterium- and Biolistic-Mediated Transformation of Maize B104 Inbred

Jennifer A. Raji, Bronwyn Frame, Daniel Little,

Methods in molecular biology

2017

35

Mouse decellularised liver scaffold improves human embryonic and induced pluripotent stem cells differentiation into hepatocyte-like cells

Maëlle Lorvellec, Federico Scottoni, Claire Crowley,

PLoS ONE

2017

29

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