Structure of the human histamine H1 receptor complex with doxepin

Tatsuro Shimamura, Mitsunori Shiroishi, Simone Weyand, +10

Nature

Molecular PharmacologySignal TransductionMolecular PhysiologyBiochemistryG Protein-coupled Receptor +8

A three-dimensional movie of structural changes in bacteriorhodopsin

Eriko Nango, Antoine Royant, Minoru Kubo, +41

Science

Structure and Molecular Mechanism of a Nucleobase–Cation–Symport-1 Family Transporter

Simone Weyand, Tatsuro Shimamura, Shunsuke Yajima, +15

Science

Nucleic Acid ChemistryInward-facing CavitiesBiochemistryProtein AssemblyProtein Folding +10

G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody

Tomoya Hino, T. Arakawa, Hiroko Iwanari, +12

Nature

Molecular PharmacologySignal TransductionG Protein-coupled ReceptorFunctional SelectivityImmunology +5

Molecular Basis of Alternating Access Membrane Transport by the Sodium-Hydantoin Transporter Mhp1

Tatsuro Shimamura, Simone Weyand, Oliver Beckstein, +7

Science

Structure and mechanism of the mammalian fructose transporter GLUT5

Norimichi Nomura, Grégory Verdon, Hae Joo Kang, +19

Nature

Molecular PhysiologyBiochemistryNatural SciencesProtein TransportCellular Biochemistry +2

Grease matrix as a versatile carrier of proteins for serial crystallography

Michihiro Sugahara, Eiichi Mizohata, Eriko Nango, +21

Nature Methods

Protein ChemistryProtein FunctionGrease MatrixProtein AssemblyBiochemistry +7

Crystal Structure-Based Virtual Screening for Fragment-like Ligands of the Human Histamine H ₁ Receptor

Chris de Graaf, Albert J. Kooistra, Henry F. Vischer, +8

Journal of Medicinal Chemistry

Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine

Kanako Kimura, Hidetsugu Asada, Asuka Inoue, +10

Nature Structural & Molecular Biology

Functional SelectivityMedicinePsychotropic MedicationMechanism Of ActionPsychopharmacology +7

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

Yasuaki Kabe, Takanori Nakane, Ikko Koike, +18

Nature Communications