Preparations of biodegradable nanospheres of water-soluble and insoluble drugs with D,L-lactide/glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior

Toshiyuki Niwa, Hirofumi Takeuchi, Tomoya Hino, +2

Journal of Controlled Release

L-lactide/glycolide CopolymerDrug Release BehaviorMicroemulsionMicro-encapsulationNano-drug Delivery +5

Crystal structure of human indoleamine 2,3-dioxygenase: Catalytic mechanism of O ₂ incorporation by a heme-containing dioxygenase

Hiroshi Sugimoto, Shun-ichiro Oda, Takashi Ôtsuki, +3

Proceedings of the National Academy of Sciences

Structural Basis of Biological N ₂ O Generation by Bacterial Nitric Oxide Reductase

Tomoya Hino, Yushi Matsumoto, Shingo Nagano, +5

Science

G-protein-coupled receptor inactivation by an allosteric inverse-agonist antibody

Tomoya Hino, T. Arakawa, Hiroko Iwanari, +12

Nature

Molecular PharmacologySignal TransductionG Protein-coupled ReceptorFunctional SelectivityImmunology +5

Crystal structure of the anion exchanger domain of human erythrocyte band 3

T. Arakawa, Takami Kobayashi-Yurugi, Yilmaz Alguel, +14

Science

Crystal StructureBiochemistryAnion Exchanger 1Protein FoldingMembrane Transport +10

Structure and mechanism of the mammalian fructose transporter GLUT5

Norimichi Nomura, Grégory Verdon, Hae Joo Kang, +19

Nature

Molecular PhysiologyBiochemistryNatural SciencesProtein TransportCellular Biochemistry +2

Crystal structures of the human adiponectin receptors

Hiroaki Tanabe, Yoshifumi Fujii, Miki Okada‐Iwabu, +21

Nature

Molecular PharmacologyCrystal StructureEngineeringBiochemistryG Protein-coupled Receptor +6

Permporometry characterization of microporous ceramic membranes

Toshinori Tsuru, Tomoya Hino, Tomohisa Yoshioka, +1

Journal of Membrane Science

Materials ScienceEngineeringPorous MembraneMembrane CharacterizationCeramic Membrane +2

Preparation of multiple unit hollow microspheres (microballoons) with acrylic resin containing tranilast and their drug release characteristics (in vitro) and floating behavior (in vivo)

Yoshiaki Kawashimà, Toshiro Niwa, Haruka Takeuchi, +2

Journal of Controlled Release

EngineeringMicrofabricationMicro-encapsulationBiofabricationPharmaceutical Technology +5

Effect of reducing-equivalent disposal and NADH/NAD on deamination of amino acids by intact rumen microorganisms and their cell extracts

Tomoya Hino, James B. Russell

Applied and Environmental Microbiology

Animal PhysiologyAmino Acid FermentationAldehyde DehydrogenaseAmino AcidsBiochemistry +13