Aruljothi Subramaniam

Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways

Radhamani Kannaiyan, Kanjoormana Aryan Manu, Luxi Chen et al. · APOPTOSIS · 2011 · 168 citations

Cancer Research, Signal Transduction, Cell Regulation +13

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of <scp>STAT3</scp>

Aruljothi Subramaniam, Muthu K. Shanmugam, Tina H. Ong et al. · British Journal of Pharmacology · 2013 · 143 citations · Full text

Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma

Kanjoormana Aryan Manu, Muthu K. Shanmugam, Tina H. Ong et al. · PLoS ONE · 2013 · 70 citations · Full text

Chemoprevention Strategy, Immunology, Pathology +24

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Aruljothi Subramaniam, Ser Yue Loo, Peramaiyan Rajendran et al. · APOPTOSIS · 2013 · 42 citations

Anthraquinone Derivative, Medicine, Apoptosis +8

Activation of human T cells with the physiological regulator of protein kinase C

Aruljothi Subramaniam, P. K. Sehajpal, V.K. Murthi et al. · Cellular Immunology · 1988 · 18 citations

Signal Transduction, Molecular Physiology, Protein Kinase C +11