Craig S. Takeuchi

Syntheses and Structure−Activity Relationships of Taxoids Derived from 14β-Hydroxy-10-deacetylbaccatin III

Iwao Ojima, John Slater, Scott D. Kuduk et al. · Journal of Medicinal Chemistry · 1997 · 113 citations

Discovery of a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR)

Craig S. Takeuchi, Byung Gyu Kim, Charles M. Blazey et al. · Journal of Medicinal Chemistry · 2013 · 65 citations · Full text

Compound 28, Drug Target, Pharmacotherapy +20

New taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells

Iwao Ojima, Pierre-Yves Bounaud, Craig S. Takeuchi et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 54 citations

Efficient Reversal Agents, Medicine, Anti-cancer Agent +8

Structural Requirements of Taxoids for Nitric Oxide and Tumor Necrosis Factor Production by Murine Macrophages

Teruo Kirikae, Iwao Ojima, Fumiko Kirikae et al. · Biochemical and Biophysical Research Communications · 1996 · 46 citations

Inflammation, Anti-inflammatory, Structural Requirements +12

Bone-targeted Src SH2 inhibitors block Src cellular activity and osteoclast-mediated resorption

Shelia M. Violette, Wei Guan, Catherine Bartlett et al. · Bone · 2001 · 40 citations

Src Cellular Activity, Osteoclast-mediated Resorption, Sclerostin +6