Craig S. Takeuchi

Syntheses and Structure−Activity Relationships of Taxoids Derived from 14β-Hydroxy-10-deacetylbaccatin III

Iwao Ojima, John Slater, Scott D. Kuduk et al. · Journal of Medicinal Chemistry · 1997 · 113 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Discovery of a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR)

Craig S. Takeuchi, Byung Gyu Kim, Charles M. Blazey et al. · Journal of Medicinal Chemistry · 2013 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

New taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells

Iwao Ojima, Pierre‐Yves Bounaud, Craig S. Takeuchi et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 54 citations

Medicine, Oncology, Pharmacology +15

Structural Requirements of Taxoids for Nitric Oxide and Tumor Necrosis Factor Production by Murine Macrophages

Teruo Kirikae, Iwao Ojima, Fumiko Kirikae et al. · Biochemical and Biophysical Research Communications · 1996 · 46 citations

Life Sciences, Cell Biology, Immunology +12

Bone-targeted Src SH2 inhibitors block Src cellular activity and osteoclast-mediated resorption

Shelia M. Violette, Catherine Bartlett, J. A. Smith et al. · Bone · 2001 · 40 citations

Medicine, Medicinal Chemistry, Pharmacology +16