Jakob J. Metzger

A Balance between Secreted Inhibitors and Edge Sensing Controls Gastruloid Self-Organization

Fred Etoc, Jakob J. Metzger, Albert Ruzo et al. · Developmental Cell · 2016 · 361 citations · Full text

Biochemistry, Medicine, Mechanism Of Action +4

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning

Sophie M. Morgani, Jakob J. Metzger, Jennifer Nichols et al. · eLife · 2018 · 192 citations · Full text

Fate Specification, Adult Stem Cell, Cell Differentiation +16

A 3D model of a human epiblast reveals BMP4-driven symmetry breaking

Mijo Simunovic, Jakob J. Metzger, Fred Etoc et al. · Nature Cell Biology · 2019 · 181 citations

Mechanobiology, Developmental Biology, Medical Biophysics +4

Self-organization of human embryonic stem cells on micropatterns

Alessia Deglincerti, Fred Etoc, Iain Martyn et al. · Nature Protocols · 2016 · 168 citations · Full text

Pattern Formation, Induced Pluripotent Stem Cell, Developmental Biology +8

Self-organizing neuruloids model developmental aspects of Huntington’s disease in the ectodermal compartment

Tomomi Haremaki, Jakob J. Metzger, Tiago Rito et al. · Nature Biotechnology · 2019 · 163 citations

Neurodegenerative Diseases, Developmental Biology, Molecular Biology +6