David Moore

A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement

Sylvie Bannwarth, Samira Ait-El-Mkadem, Annabelle Chaussenot et al. · Brain · 2014 · 490 citations · Full text

Motor Neuron Disease, Genetics, Mitochondrial Myopathy +16

<i> <scp>CHCHD</scp> 10 </i> mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis

Emmanuelle C. Genin, Morgane Plutino, Sylvie Bannwarth et al. · EMBO Molecular Medicine · 2015 · 199 citations · Full text

Mutations in the SPG7 gene cause chronic progressive external ophthalmoplegia through disordered mitochondrial DNA maintenance

Gerald Pfeffer, Gráinne S. Gorman, Helen Griffin et al. · Brain · 2014 · 174 citations · Full text

Mitochondrial Dna Maintenance, Ocular Disease, Mendelian Disorder +13

A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions

Cécile Rouzier, David Moore, Cécile Delorme et al. · Human Molecular Genetics · 2017 · 74 citations · Full text

Genetics, Pathology, Molecular Genetics +17

Evaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy

Patrick Yu‐Wai‐Man, Devorah Soiferman, David Moore et al. · Mitochondrion · 2017 · 73 citations · Full text