Satoko Kiuchi

Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes

Tomohiro Yoshida, Fumihiko Akahoshi, Hiroshi Sakashita et al. · Bioorganic & Medicinal Chemistry · 2012 · 148 citations · Full text

Biochemistry, Medicine, Rational Drug Design +7

The novel dipeptidyl peptidase-4 inhibitor teneligliptin prevents high-fat diet-induced obesity accompanied with increased energy expenditure in mice

Sayaka Fukuda-Tsuru, Tetsuhiro Kakimoto, Hiroyuki Utsumi et al. · European Journal of Pharmacology · 2013 · 49 citations

Obesity, Metabolic Syndrome, High-fat Diet-induced Obesity +10

The effect of combined treatment with canagliflozin and teneligliptin on glucose intolerance in Zucker diabetic fatty rats

Takahiro Oguma, Chiaki Kuriyama, Keiko Nakayama et al. · Journal of Pharmacological Sciences · 2015 · 26 citations · Full text

Pharmacological Characterization of T-2328, 2-Fluoro-4'-methoxy-3'-[[[(2S,3S)-2-phenyl-3-piperidinyl]amino]methyl]-[1,1'-biphenyl]-4-carbonitrile Dihydrochloride, as a Brain-Penetrating Antagonist of Tachykinin NK1 Receptor

Yumi Watanabe, Hidetoshi Asai, Taketoshi Ishii et al. · Journal of Pharmacological Sciences · 2008 · 14 citations · Full text

MEN4901/T-0128, a New Camptothecin Derivative–Carboxymethyldextran Conjugate, Has Potent Antitumor Activities in a Panel of Human Tumor Xenografts in Nude Mice

Fumiko Fujita, Masako Koike, Masahide Fujita et al. · Clinical Cancer Research · 2005 · 13 citations