Katharine L. Diehl

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

Siddhant U. Jain, J. Truman, Peder J. Lund et al. · Nature Communications · 2019 · 206 citations · Full text

ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference

Geoffrey P. Dann, Glen Liszczak, John D. Bagert et al. · Nature · 2017 · 182 citations · Full text

Chromatin, Transcriptional Regulation, Iswi Chromatin Remodellers +13

Click and chemically triggered declick reactions through reversible amine and thiol coupling via a conjugate acceptor

Katharine L. Diehl, Igor V. Kolesnichenko, Scott A. Robotham et al. · Nature Chemistry · 2016 · 113 citations

Cross-coupling Reaction, Biochemistry, Molecular Switch +7

Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase

Krupa S. Jani, Siddhant U. Jain, Eva J. Ge et al. · Proceedings of the National Academy of Sciences · 2019 · 96 citations · Full text

Acetylation blocks DNA damage–induced chromatin ADP-ribosylation

Glen Liszczak, Katharine L. Diehl, Geoffrey P. Dann et al. · Nature Chemical Biology · 2018 · 91 citations

Chromatin, Genome Instability, Dna Damage +8