Jacob T. Mitchell

Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy

Keyu Li, Joseph A. Tandurella, Jessica Gai et al. · Cancer Cell · 2022 · 178 citations · Full text

Medicine, Immunology, Oncology +17

Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24

Sophia Davidson, Chien‐Hsiung Yu, Annemarie Steiner et al. · Science Immunology · 2022 · 64 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

PanIN and CAF transitions in pancreatic carcinogenesis revealed with spatial data integration

Alexander T.F. Bell, Jacob T. Mitchell, Ashley Kiemen et al. · Cell Systems · 2024 · 51 citations · Full text

Medicine, Cell Biology, Oncology +17

Human Pancreatic Cancer Single-Cell Atlas Reveals Association of CXCL10+ Fibroblasts and Basal Subtype Tumor Cells

Ian M. Loveless, Samantha B. Kemp, Kailee M. Hartway et al. · Clinical Cancer Research · 2024 · 48 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Transfer Learning Reveals Cancer-Associated Fibroblasts Are Associated with Epithelial–Mesenchymal Transition and Inflammation in Cancer Cells in Pancreatic Ductal Adenocarcinoma

Samantha Guinn, Benedict Kinny‐Köster, Joseph A. Tandurella et al. · Cancer Research · 2024 · 44 citations · Full text

Medicine, Cell Biology, Oncology +17